ICU

  • Sedatives/Paralytics
  • Dexmedetomidine (Precedex)
  • Diprovan (Propofol)
  • Cisatracurium (Nimbex)
  • Midazolam (Versed)
  • Ketamine
  • Analgesics
  • Fentanyl
  • Vasopressors
Drug Target Effect on HR/Inotropy/Ectopy Effect on SVR Effect on CO Effect on BP Effect on PVR Main Use Safe for PIV?
InoDilators
Dobutamine ABBBB
Milrinone cAMP
Isoproterenol BBBB
Pure Vasopressors
Vasopressin V1 & V2
Phenylephrine AAAA
InoPressors
Norepinephrine AAAB
Epinephrine
Dopamine
  • InoDilators
    • Dobutamine
    • Target: ABBBB
    • 2-20 mcg/kg/min
    • High effect on SVR, BP
    • Milrinone
    • Target: cAMP
      • Decreases cAMP degradation
    • 375-0.75 mcg/kg/min SE: Hypotension, increased risk of Arrhythmias
    • Isoproterenol
    • Target: BBBB
    • 0-10 mcg/min
  • Pure Vasopressors
    • Vasopressin
    • Target: V1 and V2
    • 01-0.06 U/min
    • Phenylephrine
    • Target: AAAA
    • 40-180 mcg/min
  • InoPressors
    • Low effect on HR/Inotropy/Ectopy
    • High effect on SVR, BP
    • Norepinephrine (Levophed)
    • Target: AAAB
    • 0-40 mcg/min
    • Epinephrine
    • Target: ABBB
    • 0-20 mcg/min
    • Dopamine
    • Low
      • Target: Dopa-R
      • 1-4 mcg/kg/min
    • Medium
      • Target: ABBBD
      • 4-10 mcg/kg/min
    • High
      • Target: AAABD
      • 10-20 mcg/kg/min